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[试管婴儿]台湾 台北宏孕诊所 院长 张宏吉医师 介绍

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发表于 2018-1-8 10:30:33 |举报
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去的传统不孕症治,最人所病的便是通常需要注射大量的排卵针剂,不造成身体的担,也带给不孕症患者心理上的力。事上,多的排卵针剂刺激,除了易引Ovarian hyperstimulation syndrome (OHSS:卵巢度刺激症候群)外,所得到的卵子品也是一个大号。近年来研究发现度的排卵针剂物刺激,更有造成卵巢癌及乳癌的风险。自然周期与温和刺激法可以是一种顺应人体自然排卵机制的助孕方法。相传统不孕症治,本法不需利用度刺激卵巢来大量增加可抽取的卵子数目,只育成必要的卵子数量,因此不但可减少程中的药剂与用药剂量,降低身体所造成的担,由身体自然筛选出来的少数卵子,在品方面也较为优

近年来,由于社会文化与价值观的演代女性往往因工作、学以及找真等因素延后婚生子机,到340才开始准生儿育女,但从女性正常生理机能来看,最佳的黄金生育年却落在23-34!伴随着这样生育高象而来的往往便是必对难孕、不孕甚至是新生儿健康等问题。由于目前并无有效延人体器官老化的医学科技,一旦卵巢功能退化,以取得健康卵子甚至是濒临的不排卵情况,即便有再卓越的人工生殖技,也不免有巧妇难为无米之炊之憾!因此,利用玻璃化快速冷方法,让时间暂停,将健康卵子冻结在黄金期,做未来画生育之用,晚孕的新代女性或是有必须进行特殊医需求的女性来新机,也提供了未来幸福人生的保障。

2003纽约大学生殖医学中心的Dr.Noyes大利访问了慢速冷冻专Dr.Porcu后,决心在NYU生殖医学中心展人卵子冷,便将个大任交付于当时专任科学家的宏吉医以及来自中国的复制猫熊家刘。然而相于精子、胚胎冷已行之有年,当卵子冷仍有以突破的障碍,使得宏吉医师迟迟不敢接受这项请求。面NYU生殖医学中心主任Dr.GrifoDr.Noyes的再三托,宏吉医师终于下定决定挑战这项艰难的任
2005年,人卵子冷的成功案例被报导在美国全国公司电视NBC TV
并且在2002年至2007连续六年在人生殖域的最高威,美国生殖医学学会表了13篇的研究告。

日本国内日报发行量第二名的朝日新2013年以全版面介本院
本院于2014年接受日本TBS道「NEWS 23」新闻节目采访该节针对在本院借卵之日本患者身采访制作专题报导
2016年,位于日本广岛报社所行的报纸「中国新」亦大幅报导本院借卵治成果,一为话题
2017年登上洲第一大读卖条新报导日本人来台湾宏孕所治卵子情况。显现日媒重日人到台治情况并大幅报导

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宏吉医的学经历

1986-1993 台湾 台大医学系

1995-2001 台湾 台大医院妇产

2001-2007 美国 纽约大学医学院生殖医学中心任全科学

宏吉医登上NBCNYU纽约大学生殖医学中心冷卵子报导
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台湾 台北宏孕诊所环境影片
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张宏吉医师于美国生医学年会发表照片

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宏吉医的研究成

· 术论

· Chang HC, Grifo J, McCaffrey, Krey LC, Noyes N. (2007 ASRM) Using certain commercially available glass-bottomed dish with paraffin oil impacts the embryonic development of oocytes. [Abstract] Fertility & Sterility. 2007; 88: S310 (#J0130599).

· Chang, HC; Liu, H; Noyes, N; Meng, L; Krey, L; Grifo, J. “Down regulatory effects of retinoid signaling on murine and human embryonic Oct-4 gene expression [Abstract]”. Fertility & sterility. 2006; 86: S219 (#J0123967)

· Noyes, N; Chang, HC; Liu, H; Labella, P; Meng, L; Grifo, JA. “Presence of meiotic spindle predicts embryo competence following oocyte cryopreservation [Abstract]”. Fertility & Sterility. 2006; 86: S64 (#J0123958) Chang, HC; Noyes, N; Lee, TL; Chin, A; Krey, L; Grifo, J. “Independent and sequential expression of Oct3A and Oct3B transcription factors in human preimplantation embryos [Abstract]”. Fertility & Sterility. 2006; 86: S220 (#J0123968)

· Chang, HC; Grifo, J; Labella, P; Ampeloquio, E; Adler, A; Krey, L. “Oct3A and Oct3B immunostaining patterns in human 3PN zygotes and aneuploid embryos diagnosed by preimplantation genetic diagnosis (PGD): Embryonic chromosome status can be independent of developmental competence [Abstract]”. Fertility & Sterility. 2006; 86: S220 (#J0123969)

· Keegan DA, Krey LC, Chang HC and Noyes N. (2007) Increased risk of pregnancy-induced hypertension between in young recipients of oocyte donation. Fertility and Sterility. Apr;87(4):776-81.

· Chang, HC; Liu, H; Zhang, J; Grifo, J; Krey, LC. “Ooplasnnic factors are responsible for the developmental defects observed when immature cumulus-enclosed mouse oocytes are denuded prior to maturation [Abstract]”. Fertility & Sterility. 2004; 82: S10 (#J0078695)

· Chang HC, Liu H, Zhang J, Grifo J, Krey LC. (2005) Developmental incompetency of denuded mouse oocytes undergoing maturation in vitro is ooplasmic in nature and is associated with aberrant Oct-4 expression. Human Reproduction, July, Vol. 20, No.7, 1958-1968.

· Chang, HC; Liu, H; Zhang, J; Grifo, J; Krey, LC. “Ooplasnnic factors are responsible for the developmental defects observed when immature cumulus-enclosed mouse oocytes are denuded prior to maturation [Abstract]”. Fertility & Sterility. 2004; 82: S10 (#J0078695)

· Liu H, Chang HC, Zhang J, Grifo J, Krey LC. Metaphase II nuclei generated by germinal vesicle transfer in mouse oocytes support embryonic development to term. Human Reproduction, 2003 Sep;18(9):1903-1907.

· Chang HC, Liu H, Blaszczyk A, Grifo J, Krey LC (2003) Influences of mouse strain and culture media on in vitro maturation and embryogenesis of denuded mouse oocytes. Fertility and Sterility, Vol.80 3S S266. (#J0101655)

· Liu H, Krey LC, Zhang J, Chang HC, Grifo JA (2002) Germinal vesicle xeno-transfer between mouse and human oocytes: a model to study ooplasmic influences on meiotic division. Fertility and Sterility, September Vol.76 No. 3S O-202.

· Chang HC, Liu H, Grifo JA, Krey LC (2002) Influences of Gonadotroping stimulation on in vitro maturation and embryogenesis of denuded mouse oocytes. Fertility and Sterility, September Vol.76 No. 3S P-458.

· Chang HC, Wu MY, Ho HN, Yang YS (1996) Delayed delivery of surviving triplet after fetal reduction and spontaneous abortion. Journal of Formos Medical Association. Nov;95(11):881-4. (original paper)

 

· 美国生殖医学年会演

· Noyes N, Chang HC, Labella P, McCaffrey C, Fino E, Grifo J. (2007 ASRM) Visualization of meiotic spindle predicts usefulness of female gamates in an oocyte cryopreservation program.

· Chang HC, Grifo J, McCaffrey, Krey LC, Noyes N. (2007 ASRM) Using certain commercially available glass-bottomed dish with paraffin oil impacts the embryonic development of oocytes.

· Chang HC, Grifo J, Ampeloquio E, LaBella P, Adler A and Krey LC. (2006 ASRM) Oct3A and Oct3B immunostaining patterns in human 3PN zygotes and aneuploid embryos diagnosed by preimplantation genetic diagnosis (PGD): embryonic chromosome status can be independent of developmental competence.

· Chang HC, Noyes N, Lee TL, Chin A, Krey LC and Grifo JA. (2006 ASRM) Independent and sequential expression of Oct3A and Oct3B transcription factors in human preimplantation embryos.

· Chang HC, Liu H, Noyes N, Meng L, Krey LC and Grifo J. (2006 ASRM) Down regulatory effects of retinoid signaling on murine and human embryonic Oct-4 gene expression. Liu H, Labella P, Chang HC, Noyes N, Krey LC and Grifo JA. (2006 ASRM) Vitrification influence on the viability of human and mouse oocytes is temperature relevant.

· Grifo J, Labella P, Licciardi F, Chang HC, Liu H and Noyes N. (2006 ASRM) Clinical results of an oocyte cryopreservation program. Noyes N, Chang HC, Meng L, Liu H, Labella P, Grifo J (2006 ASRM) Presence of meiotic spindle predicts embryo competence following oocyte cryopreservation.

· Chang HC, Liu H, Zhang J, Grifo J, Krey LC. (2005 SRM) Vitrification of metaphase II oocytes impacts Oct-4 expression during subsequent preimplantation development. Oral presentation in Montreal, 61th Annual Meeting of the American Society for Reproductive Medicine.

· Chang HC, Liu H, Zhang J, Grifo J, Krey LC. (2004 ASRM) Ooplasmic factors are responsible for the developmental defects observed when immature cumulus-enclosed mouse oocytes are denuded prior to maturation. Oral presentation in Philadelphia, 60th Annual Meeting of the American Society for Reproductive Medicine.

· Chang HC, Liu H, Blaszczyk A, Grifo JA, Krey LC (2003 ASRM) Influences of mouse strain and culture media on in vitro maturation and embryogenesis of denuded mouse oocytes. Fertility and Sterility, Vol.80 3S S266.

· Chang HC, Liu H, Grifo J, Krey LC (2002 ASRM) Influences of gonadotropin stimulation on in vitro maturation and embryogenesis of denuded mouse oocytes. Poster presentation in Orlando, 59th Annual Meeting of the American Society for Reproductive Medicine.

· Liu H, Krey LC, Zhang J, Chang HC, Grifo JA (2002 ASRM) Germinal vesicle xeno-transfer between mouse and human oocytes: a model to study ooplasmic influences on meiotic division. Fertility and Sterility, September 2002 Vol.76 No. 3S O-202. 58th Annual Meeting of the American Society for Reproductive Medicine.

 

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六级宝宝 | 发表于 2018-1-27 14:51:29
要是会想到自己有一天怀孕都会这么痛苦,说什么我也不会流产了,已经尝试了无数次人受、试管,中药也是一直在调理,实在不知道还能怎么办,难道要去领养一个不属于自己的宝宝吗
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十级宝宝 | 发表于 2分钟前
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九级宝宝 | 发表于 2018-3-7 11:54:08
回复 大枕头头
要是会想到自己有一天怀孕都会这么痛苦,说什么我也不会流产了,已经尝试了无数次人受、试管,中药也是一直 ...

亲,看您这么难过,真的很为您感到不舍(抱)
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